Eif2s1 sirna

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August undefined, 2024

WebeIF2 α Antibodies for analysis of cellular responses to eIF2 α si/shRNA Gene Silencers ChemCruz™ Chemical Inhibitors for functional analysis of cellular responses to eIF2 α Click on image or enlarge button to enlarge RNAi-directed mRNA Cleavage Gene Info Description 10 µM, 50-100 transfections WebEIF2S1 is one subunit of the translation initiation factor EIF2, which catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to …

Recombinant Anti-EIF2S1 (phospho S51) antibody [E90] (ab32157)

WebFor the independent antibodies validation the evaluation is based on comparison of the staining of two (or more) independent antibodies directed towards independent epitopes … WebEIF2S1. The antibodies are designated mAB for monoclonal and pAb for polyclonal. The release of the Human Protein Atlas in which the antibody was first published. All assays through which the antibody has been validated. Assays&annotation provide a detailed description of the different assays. dashlane italiano

EIF2S1 - Antibodies - The Human Protein Atlas

WebPhosphorylation of the eukaryotic initiation factor 2 (eIF2) α subunit is a well-documented mechanism to downregulate protein synthesis under a variety of stress conditions. eIF2 binds GTP and Met-tRNAi and transfers Met-tRNA to the 40S subunit to form the 43S preinitiation complex (1,2). eIF2 promotes a new round of translation initiation by … WebIn acute liver injury, inhibiting eIF2alpha (EIF2s1) dephosphorylation protects injured hepatocytes and reduces hepatocyte proliferation. The protein kinase RNA-like endoplasmic reticulum kinase pathway was activated followed by increased phosphorylation of eukaryotic initiation factor-2 alpha (eIF2alpha). WebAnti-EIF2S1 (phospho S51) antibody [E90] (ab32157) only detects eIF-2a phosphorylated on Serine 51. Tested applications Suitable for: WB, IHC-P, Dot blot more details Unsuitable for: Flow Cyt,ICC/IF or IP Species reactivity Reacts … marni nicola

SANTA CRUZ BIOTECHNOLOGY, INC. eIF2a (D-3): sc-133132

Direct interaction between STAT3 and EIF2AK2 controls fatty acid ...

WebAll lanes : Anti-EIF2S1 (phospho S51) antibody [E90] (ab32157) at 1/1000 dilution Lane 1 : RAW 264.7 (Mouse Abelson murine leukemia virus-induced tumor macrophage) Whole … The protein encoded by this gene is the alpha (α) subunit of the translation initiation factor eIF2 protein complex which catalyzes an early regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA (Met-tRNAi ) to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (α, 36 kD, this article), beta (β, 38 kD), and gamma (γ, 52 kD). The rate of formation of the ternary co… dashlane invoiceWebCytoplasmic STAT3 normally interacts with the eukaryotic translation initiation factor 2, subunit 1α, 35kDa (EIF2S1/eIF2α) kinase 2/protein kinase, RNA-activated (EIF2AK2/PKR), a sensor of double-stranded RNA. This interaction, which could be recapitulated using recombinant proteins in pull-down experiments, involves the catalytic domain of ... marni milano uffici

"WebNX_O75807 - PPP1R15A - Protein phosphatase 1 regulatory subunit 15A - Function. Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the … " - Eif2s1 sirna

Eif2s1 sirna

Recombinant Anti-EIF2S1 (phospho S51) antibody [E90] (ab32157)

WebAb5369 staining EIF2S1 in human placenta. Staining is localised to the cytoplasm. Left panel: with primary antibody at 2 ug/ml. Right panel: isotype control. Sections were stained using an automated system DAKO Autostainer Plus , at room temperature. Sections were rehydrated and antigen retrieved with the Dako 3-in-1 AR buffer citrate pH 6.0 in ... WebPolyclonal Antibody for studying EIF2S1/eIF2-alpha (Ser52) phosphate. Cited in 930 publications. Validated for Western Blotting, Simple Western™. Available in 2 sizes. Highly specific and rigorously validated in-house, …

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WebJan 23, 2007 · EIF2S1/eIF-2-alpha is a key component of the integrated stress response (ISR), required for adaptation to various stress: phosphorylation by metabolic-stress sensing protein kinases (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2) in response to stress converts EIF2S1/eIF-2-alpha in a global protein synthesis inhibitor, … WebMar 21, 2024 · EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit Alpha) is a Protein Coding gene. Diseases associated with EIF2S1 include Vaccinia and Epiphyseal …

WebJun 24, 2024 · Ferroptosis is a newly recognized process of cell death, which is different from other forms of cell death in morphology, biochemistry, and genetics, and has played a vital role in cancer biology. This study aimed to identify a ferroptosis-related gene signature associated with LUAD prognosis. WebThe protein encoded by this gene is the alpha (α) subunit of the translation initiation factor eIF2 protein complex which catalyzes an early regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA (Met-tRNA iMet) to 40S ribosomal subunits.

WebProduct Description EIF2S1 siRNA is a pool of three individual synthetic siRNA duplexes designed to knock-down human EIF2S1 mRNA expression. Each siRNA is 19-25 bases … WebMISSION ® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing …

WebApr 4, 2024 · EIF2A is a widely used alternative name for eukaryotic translation initiation factor 2 subunit alpha (EIF2S1), which can be confused with the official symbol for …

WebApr 23, 2024 · Eif2s1 S51A mice were maintained on a C57BL/6J background. For slice electrophysiology, homozygous IRES ChAT-Cre mice were crossed with homozygous Ai3 reporter mice on the Rosa26 locus (JAX: 007903) to yield double heterozygotes with EYFP-expressing CINs. Juvenile [postnatal day 21 (P21) to P60] male and female mice were … marnini scale ascensoriWeb沈宝玉，杨根梦，李媛媛，刘柳，黄俭，曾晓锋，李利华（昆明医科大学法医学院，云南昆明 650500）可卡因又称古柯碱，是古柯树的天然植物产物，由奥地利化学家纽曼于1859 年提纯并命名。 marnin pasticceriaWebEIF2S1 is one subunit of the translation initiation factor EIF2, which catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. marni omotesandoWebSee other EIF2S1 SIRNA Assays › Gene Symbol: Eif2s1 Gene Name: eukaryotic translation initiation factor 2, subunit 1 alpha Gene Aliases: 0910001O23Rik, 2410026C18Rik, 35kDa, Eif2a, eIF2alpha Chromosome Location: Chr.12: 78862072 - 78887010 on Build GRCm38 UniGene ID: Mm.196220 Species: Mouse. siRNA ID ... marni occhialiWeb目的通过表征自噬相关基因(args)在胰腺癌(paad)中的表达模式和预后,寻找与胰腺癌免疫治疗预后不良相关的候选基因.方法从人类自噬数据库(hadb)和基因集富集分析(gsea)网站获得566个自噬相关基因,通过gepia、kaplan-meier plotter和cbioportal数据库检测胰腺癌患者 … dashlane ios autofillWebMay 10, 2024 · In turn, sustained HSPB1 expression activates eukaryotic translation initiation factor 2 subunit alpha (EIF2S1)/activating … marni official siteWebKnock- down of EIF2AK4 markedly blocked the phosphorylation levels of EIF2S1 and protein levels of ATF4 in Beas-2B cells infected with WT PA14 or treated by PYO ( Fig. 4D and E), indicating that ... marni occasional chair