WebThis antibody is phospho specific for dual phosphorylated pS423 and pS425 of Smad3. Stimulation with 2 ng/ml TGF-beta for 1 hour is suggested. ... Negligible reactivity is seen against other phosphorylated Smad family members. A BLAST analysis was used to suggest cross reactivity with Smad3 from human, Xenopus laevis, Xenopus tropicalis ... WebJan 15, 2003 · The phosphorylation of Smad2 on Ser465/467 and subsequent dimerization with Smad4 and translocation to the nucleus are known to be required for signal …
Phospho-Smad4 (T277) ELISA Kit (ab279931) Abcam
WebSmad2 ubiquitously expressed transcription factor phosphorylated and activated by TGF-beta receptor-type kinases. Participates in a wide range of critical processes including morphogenesis, cell-fate determination, proliferation, differentiation and apoptosis. Sequence: P84022 SMAD3_HUMAN: Protein BLAST With NCBI / ExPASy / Uniprot WebFig. S1. Endogenous BMP activity in the gut and dorsal mesentery during looping. ( A) Phospho-Smad staining of the dorsal mesentery from E6 through E20. (Scale bar: 100 µm.) ( B) In situ hybridization for bmp2 in the dorsal mesentery and gut tube from E6 through E20. [Scale bar (E6–E10) and (E12–E20): 100 µm.] kaiser permanente of texas
Phospho-Smad5 (Ser463,Ser465) Antibody from Thermo Fisher …
TGF-B ligands bind receptors consisting of type 1 and type 2 serine/threonine kinases, which serve to propagate the signal intracellularly. Ligand binding stabilizes a receptor complex consisting of two type 1 receptors, and two type 2 receptors. Type 2 receptors then can phosphorylate type 1 receptors at locations on the GS domain, located N-terminally to the type 1 kinase domain. This phosphorylation event activates the type 1 receptors, making them capable of further propagatin… WebZoom Anti-phospho-Smad3 (Ser423/425) Antibody is a Rabbit Polyclonal Antibody for detection of phospho-Smad3 (Ser423/425) also known as MAD Mothers against DPP … WebZoom Anti-phospho-Smad3 (Ser423/425) Antibody is a Rabbit Polyclonal Antibody for detection of phospho-Smad3 (Ser423/425) also known as MAD Mothers against DPP homolog 3 & has been validated in WB. Anti-phospho-Smad3 (Ser423/425) Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available … lawnboy 10361 drive belt