WebSAIGE SAIGE is an R package with Scalable and Accurate Implementation of Generalized mixed model (Chen, H. et al. 2016). It accounts for sample relatedness and is feasible for … Web11 hours ago · Using single-cell RNA sequencing, researchers identified 12 atherosclerosis-associated cell states and found that Vcam1+ smooth muscle cell state contributed the most to the genetic heritability of coronary artery disease. A hybrid polygenic risk score (PRS) that considers cell-type-specific regulatory elements demonstrated improved …
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WebDec 22, 2024 · Brief Description. METAL is a tool for meta-analysis genomewide association scans. METAL can combine either (a) test statistics and standard errors or (b) p-values … WebDosage Sensitivity Tools. The ClinGen Dosage Sensitivity tools aid the curation process that collects evidence supporting/refuting the haploinsufficiency and triplosensitivity of genes and genomic regions. The interface is currently restricted to … durazno en su jugo
SAIGE on Biowulf - National Institutes of Health
WebGeneMarker ® - The Biologist Friendly Software. GeneMarker® software is a unique genotype analysis software which integrates new technologies enhancing the speed, accuracy and ease of analysis. Biologist-friendly, the software is compatible with outputs from all major sequencing systems. Incorporated tools include Kinship Analysis of Wild ... http://www.nealelab.is/uk-biobank WebCDPOP is a spatially-explicit simulator of gene-flow in complex landscapes to explain observed population responses and provide a foundation for landscape genetics. BayeSSC (Bayesian Serial SimCoal) is a Bayesian modification of SIMCOAL 1. KERNELPOP This package creates a individual-based population genetic simulation. realtime emoji usage